The Magic School Bus and the Science Fair Expedition is the eleventh book in the original book series.
The students are agonizing over the upcoming science fair. A field trip to the nearby science museum provides inspiration and in the galleries. They discover a model school bus which conveys them back in time where they meet famous scientists such as Galileo and the Curies and witness pivotal discoveries.
- This book is the first one in the original series to include 21st century technology such as flat panel monitors when it comes to computers.
- If the Ms. Frizzle's Adventures subseries from after Explores the Senses is not counted, this is the first book to be released in the 21st century, and in the 201st decade (2000s).
- This is the second book to feature the character versions of Joanna Cole and Bruce Degen, with the first being And the Electric Field Trip. Cole and Degen are workers at Jo's Diner in the previously mentioned book.