Season 1[]
| Episode | Number | Topic | Guest Star |
|---|---|---|---|
| Gets Lost in Space | 1 | Solar System | N/A |
| For Lunch | 2 | Digestion | N/A |
| Inside Ralphie | 3 | Germs | Dr. Tennelli |
| Gets Eaten | 4 | Food Chains | N/A |
| Hops Home | 5 | Habitats | Bella |
| Meets the Rot Squad | 6 | Decomposition | N/A |
| All Dried Up | 7 | Desert Adaptation | N/A |
| In the Haunted House | 8 | Sound | Professor Cornelia C. Contralto II |
| Gets Ready, Set, Dough | 9 | Kitchen Chemistry | The Baker |
| Plays Ball | 10 | Forces | N/A |
| Goes to Seed | 11 | Seeds | Mr. Seedplot |
| Gets Ants in Its Pants | 12 | Ants | N/A |
| Kicks Up a Storm | 13 | Weather | N/A |
Season 2[]
| Episode | Number | Topic | Guest Star |
|---|---|---|---|
| Blows Its Top | 1 | Volcanoes | N/A |
| Flexes Its Muscles | 2 | Body Mechanics | R.U. Humerus |
| The Busasaurus | 3 | Dinosaurs | Carmina Skeledon |
| Going Batty | 4 | Bats | Dr. Tennelli, Mr. Terese, Mrs. Franklin, Mr. Perlstein, Mr. Ramon |
| Butterfly and the Bog Beast | 5 | Butterflies | N/A |
| Wet All Over | 6 | Water | Tiffany |
| In a Pickle | 7 | Microbes | N/A |
| Revving Up | 8 | Engines | Mr. Junkett |
| Taking Flight | 9 | Flight | N/A |
| Getting Energized | 10 | Energy | Mikey Ramon |
| Out of This World | 11 | Space Rocks | Dorothy Ann's Mother, Evan |
| Cold Feet | 12 | Warm/Cold-Blooded | Harry Herp |
| Ups and Downs | 13 | Floating and Sinking | Mrs. Li, Gerri Poveri |
Season 3[]
| Episode | Number | Topic | Guest Star |
|---|---|---|---|
| In a Beehive | 1 | Honeybees | N/A |
| In the Arctic | 2 | Heat | Harry Arm |
| Spins a Web | 3 | Spiders | General Araneus |
| Under Construction | 4 | Structures | Mrs. LiWilliam Li |
| Gets A Bright Idea | 5 | Light | N/A |
| Shows and Tells | 6 | Archaeology | Show Announcer |
| Makes a Rainbow | 7 | Color | Mr. Ruhle |
| Goes Upstream | 8 | Migration | N/A |
| Works Out | 9 | Circulation | Garth Sinew |
| Gets Planted | 10 | Photosynthesis | N/A |
| In the Rainforest | 11 | Rainforest Ecology | Inspector 47 |
| Rocks and Rolls | 12 | Water Erosion | Ashley Walker-Club Dupree |
| Holiday Special | 13 | Recycling | Katrina Eloise "Murph" Murphy |
Season 4[]
| Episode | Number | Topic | Guest Star |
|---|---|---|---|
| Meets Molly Cule | 1 | Molecules | Molly Cule |
| Cracks a Yolk | 2 | Eggs | Mr. Ruhle |
| Goes to Mussel Beach | 3 | Tidal Zones | N/A |
| Goes on Air | 4 | Air Pressure | N/A |
| Gets Swamped | 5 | Wetlands | N/A |
| Goes Cellular | 6 | Cells | N/A |
| Sees Stars | 7 | Stars | Horace Scope |
| Gains Weight | 8 | Gravity | Mr. Ruhle |
| Makes a Stink | 9 | Smells | Flora Whiff |
| Gets Charged | 10 | Electricity | N/A |
| Gets Programmed | 11 | Computers | Mr. Ruhle Mikey Ramon Mr. McClean |
| In the City | 12 | City Critters | N/A |
| Takes a Dive | 13 | Coral Reefs and Symbiosis | N/A |